NSE Antibodies

The glycolytic enzyme enolase (2-phospho-D-glycerate hydrolase, EC 4.2.1.11) exists as several dimeric isoenzymes (αα,αβ, αγ, ββ and γγ).

The αγ and γγ-enolase isoenzymes are also known as neuron-specific enolase (NSE) as these isoenzymes were initially detected in neurons and neuroendocrine cells.

Antibodies specific for the γ-subunit are suitable for the serological determination of NSE (ie, the γγ- and αγ - isoforms of enolase).

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